I was recently attempting to uninstall an application on Windows 7 Professional when I received the below error message :
“Error opening installation log file. Verify that the specified location exists and is writable.” error when attempting to uninstall an application
This is apparently a known issue with the mentioned operating system and the workaround is to restart the explorer.exe process within Task Manager. This is due to the installer service attempting to write to ‘C:\Windows\System32’ and addressing the directory as a file.
To confirm, following a restart I was able to uninstall/install applications without experiencing this issue.
For full details see – http://support.microsoft.com/kb/2564571